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Antibiotics are powerful tools in modern medicine, designed to treat bacterial infections that can’t be resolved by the body’s immune system alone. While they save lives and prevent severe complications, overuse or misuse can lead to antibiotic resistance and disruptions to your microbiome. This article will help you understand when antibiotics are truly necessary, how to care for your microbiome during and after treatment, and how natural remedies can support your immune system. 

Understanding The Difference Between Viral and Bacterial Infections 

Knowing whether an infection is viral or bacterial is key to determining if antibiotics are appropriate. Although symptoms of viral and bacterial infections can overlap, their causes and treatments differ significantly.  

To learn more about illness and the immune system in children, read this article: Does My Child Get Sick Too Often? Understanding Sickness Frequency in Children 

What Are Bacterial Infections? 

Bacterial infections occur when harmful bacteria invade the body, multiply, and cause illness (1). The principal modes of transmission of bacterial infection include direct contact with an infected person, inhalation of airborne droplets from coughing or sneezing, touching of contaminated surfaces, insect bites (such as ticks or mosquitoes), or contaminated food or water (1). These infections range from mild to severe, with some resolving on their own and others requiring antibiotics to prevent serious complications. 

What Are Viral Infections? 

Viral infections are caused by viruses, smaller microorganisms that rely on the body’s cells to replicate (2). Viruses are commonly spread through close contact with an infected person, airborne droplets, contaminated surfaces, or sharing of personal items. The body’s immune system usually clears viral infections on its own, though antiviral medications may be used for specific viruses (2).

Antibiotics do not resolve viral infections because they are specifically designed to target bacteria, not viruses.  

Bacteria magnified under a telescope.

When Are Antibiotics Truly Necessary? 

Antibiotics are necessary for bacterial infections that are severe, pose a risk of complications, or are unlikely to resolve without intervention (3). For instance, bacterial pneumonia often requires antibiotics, as it can lead to respiratory failure or sepsis if untreated (4).  

Bacterial meningitis is a life-threatening condition that requires immediate antibiotic treatment. Symptoms include severe headache, neck stiffness, fever, and sensitivity to light. Without prompt treatment, bacterial meningitis can result in permanent damage or death (5). 

Infections like sepsis, a condition in which bacteria enter the bloodstream and cause systemic inflammation, also demand urgent antibiotic therapy. Signs of sepsis include high or low body temperature, confusion, rapid heart rate, and difficulty breathing (6). 

That said, some bacterial infections can also be self-limiting (3), meaning they may improve without antibiotics, though antibiotic treatment is sometimes still recommended to prevent complications. 

Strep throat, caused by Streptococcus pyogenes, is one example. While it can technically resolve on its own, antibiotics are often prescribed to prevent potential complications, such as rheumatic fever or kidney inflammation (7).  

Bacterial ear infections, or otitis media, are another example. Many mild cases resolve without antibiotics, even if the cause is bacterial. However, if symptoms persist or include severe pain or high fever, antibiotics may be necessary (8). 

Mild bacterial sinus infections often resolve on their own as well. While antibiotics are generally unnecessary for most sinus infections, prolonged symptoms lasting more than 2-3 days or worsening after initial improvement may indicate a need for treatment (9). 

Viral Infections That Turn Into Bacterial Infections 

Viral infections can sometimes lead to secondary bacterial infections (10,11). It is thought that this is in part because viruses can temporarily damage the protective mucosal lining in the nose, throat, or lungs, making it easier for bacteria to invade (11). Increased mucus production during a viral illness can create a stagnant moist environment where bacteria thrive, leading to infections like sinusitis or ear infections. 

For example, a cold or flu could cause mucus buildup in the sinuses or middle ear. If this mucus doesn’t drain properly, bacteria could multiply, resulting in bacterial sinusitis or otitis media. Additionally, the immune system, already fatigued from fighting the virus, may struggle to combat bacterial invaders. One indicator that a secondary infection like pneumonia or sinusitis may be developing is that symptoms improve and then come back worse with a fever (12).  

To learn more, read this article: Bronchitis, Bronchiolitis, Pneumonia, & Mycoplasma Pneumonia – An Integrative Perspective 

Dispelling the Myth About Snot Color 

Mucus serves an essential role in your respiratory system, trapping dust, allergens, and pathogens to keep your airways clear. A common misconception is that the color of nasal mucus (snot) can indicate whether an infection is bacterial or viral. For example, many people believe that green or yellow mucus indicates a bacterial infection, while clear mucus suggests a viral cause. While snot color can provide some clues about what’s happening in your child’s body, it’s not a reliable indicator of whether an infection requires antibiotics. Here are some general tips when it comes to interpreting snot color in your little one: 

  1. Clear Mucus: Often associated with allergies or the early stages of a viral infection, clear mucus indicates a healthy baseline or an increase in mucus production without significant immune activity. 
  2. White Mucus: White mucus may result from mild nasal inflammation, which thickens the mucus and slows its movement. 
  3. Yellow or Green Mucus: The greenish hue comes from myeloperoxidase, an enzyme released by white blood cells as they fight infections. It doesn’t mean the infection is bacterial; viral infections can also produce green or yellow mucus (13). 
  4. Red or Brown Mucus: Blood-tinged mucus may appear if your nasal passages are irritated or dry, especially after frequent nose blowing. 

When to Seek Care: Smelly thick mucus or symptoms like persistent fever, facial pain, or worsening illness may signal a more serious infection that requires medical attention.  

A child with a fever lays on a bed with a thermometer in her mouth.

When to See a Doctor  

While many infections resolve on their own, certain symptoms indicate the need for medical attention and possibly antibiotics: 

  • High or Persistent Fever: A fever over 102°F lasting more than three days or recurring after improvement may suggest a bacterial infection. 
  • Fever in Newborns: A fever of 100.4°F or higher in babies under three months old requires immediate medical evaluation, as newborns are more vulnerable to serious infections. 
  • Worsening Symptoms After Improvement: Symptoms that return with fever or increased mucus may indicate a secondary bacterial infection like sinusitis or pneumonia. 
  • Severe Pain: Persistent ear, face, or chest pain could signal bacterial infections like otitis media or sinusitis. 
  • Difficulty Breathing: Rapid breathing, wheezing, or shortness of breath requires urgent care. 
  • Severe Headache or Neck Stiffness: These, along with fever or light sensitivity, may indicate bacterial meningitis. 
  • Localized Redness, Swelling, or Pus: Redness or swelling with pus suggests a skin infection needing treatment. 
  • Lethargy or Unresponsiveness in Children: Unusual drowsiness, difficulty waking, or refusal to eat or drink warrants immediate medical attention. 

Always trust your instincts and seek care if symptoms are severe, persist, or worsen unexpectedly, especially in young infants. 

What is Antibiotic Resistance, and Why Does it Matter? 

Antibiotic resistance occurs when bacteria evolve to withstand the effects of antibiotics, making once-treatable infections more difficult, or even impossible, to manage (14). This growing global health concern is driven by the overuse and misuse of antibiotics, such as prescribing them for viral infections or using them too frequently (14). The consequences are serious: longer illnesses, more severe infections, higher healthcare costs, and fewer effective treatment options. Antibiotic resistance also increases the risks associated with routine medical procedures, such as surgeries, due to the threat of untreatable infections.  

Natural Remedies to Support Immune Health 

Nature offers several remedies that can support your body’s ability to fight infections. These can be helpful for mild illnesses or as complements to conventional treatments, but do not replace modern antibiotics. Some favorites include: 

Garlic: Allicin is a component in garlic, which may support general wellness (15). Garlic can be taken fresh, cooked into meals, or in supplement form. 

Goldenseal: A perennial herb native to North America, traditionally used to support immune health (16) and soothe mucous membranes. Available in herbal glycerite form and capsules. 

Colloidal Silver: A suspension of microscopic silver particles in liquid used internally and/or topically to support the natural healing process (17).  

Manuka Honey: Supports wellness and can be applied to minor cuts (18). Choose products with a UMF rating. 

Important Note: While natural remedies can be effective for mild or early-stage infections, they are not substitutes for antibiotics. 

Caring for Your Microbiome During and After Antibiotics 

Antibiotics don’t just target harmful bacteria—they also disrupt the balance of beneficial bacteria in your microbiome by killing both harmful and helpful microbes (3). This can reduce the diversity of good bacteria needed for digestion, vitamin production, and immune support. It may also impact the gut barrier, potentially leading to increased intestinal permeability (19) (“leaky gut“) and impacting the inflammatory response (20). 

To support recovery, consider consuming probiotics, fermented foods, and fiber-rich meals to help restore gut health during and after antibiotic use. 

1. Probiotics 

Take probiotics* with strains like Saccharomyces Boullardi and Bifidobacterium Bifidum to maintain gut health (21). 

*Space probiotics 2–3 hours apart from antibiotics (22). 

2. Prebiotics 

Feed beneficial bacteria with prebiotic rich foods like garlic, onions, bananas, and asparagus (23). 

3. Nutrient-Dense Foods 

Focus on whole, unprocessed foods to support recovery and overall health. 

4. Hydration 

Get plenty of fluids (filtered water, broth, coconut water, herbal tea, hydration drinks) to support digestion and immune function. 

5. Herbs  

Herbal support can be really useful during times when antibiotics are necessary. Ginger and black seed oil are two favorites. Learn more here: How To Avoid Side Effects of Antibiotics Using Natural Medicine 

To learn more about restoring gut health, read this article: Restoring Gut Health After Antibiotics: A Guide For Families 

Summary 

Antibiotics are essential for treating serious bacterial infections but should be used responsibly to avoid overuse and antibiotic resistance. Understanding the difference between bacterial and viral infections helps ensure antibiotics are only used when truly necessary. Natural remedies like garlic, goldenseal, and Manuka honey can support immune health but should complement, not replace, antibiotics. During and after antibiotic treatment, it’s important to care for your microbiome by incorporating probiotics, prebiotics, and nutrient-dense foods to restore gut balance. By using antibiotics wisely and supporting your body naturally, you can maintain health while minimizing potential risks. 

References:  

  1. Doron S, Gorbach SL. Bacterial Infections: Overview. International Encyclopedia of Public Health. 2008:273–82. doi: 10.1016/B978-012373960-5.00596-7. Epub 2008 Aug 26. PMCID: PMC7149789. 
  2. Baron S, Fons M, Albrecht T. Viral Pathogenesis. In: Baron S, editor. Medical Microbiology. 4th edition. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 45. Available from: https://www.ncbi.nlm.nih.gov/books/NBK8149/ 
  3. Centers for Disease Control and Prevention. (n.d.). Healthy habits: Antibiotic do’s and don’ts. Centers for Disease Control and Prevention. https://www.cdc.gov/antibiotic-use/about/index.html  
  4. Sattar SBA, Nguyen AD, Sharma S. Bacterial Pneumonia. [Updated 2024 Feb 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK513321/ 
  5. Runde TJ, Anjum F, Hafner JW. Bacterial Meningitis. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470351/ 
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  7. Kanwal S, Vaitla P. Streptococcus Pyogenes. [Updated 2023 Jul 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554528/ 
  8. Centers for Disease Control and Prevention. (n.d.). Ear infections: About ear infections. U.S. Department of Health and Human Services. Retrieved January 24, 2025, from https://www.cdc.gov/ear-infection/about/index.html 
  9. Centers for Disease Control and Prevention. (n.d.). About sinus infections. U.S. Department of Health and Human Services. Retrieved January 24, 2025, from https://www.cdc.gov/sinus-infection/about/index.html 
  10. Beadling C, Slifka MK. How do viral infections predispose patients to bacterial infections? Curr Opin Infect Dis. 2004 Jun;17(3):185-91. doi: 10.1097/00001432-200406000-00003. PMID: 15166819. 
  11. Floret D. Co-infections virus-bactéries [Virus-bacteria co-infections]. Arch Pediatr. 1997 Nov;4(11):1119-24. French. doi: 10.1016/s0929-693x(97)88982-8. PMID: 9488749. 
  12. American Academy of Pediatrics. (2013). Clinical practice guideline for the diagnosis and management of acute bacterial sinusitis in children aged 1 to 18 years. Pediatrics, 132(1), e262–e280. https://doi.org/10.1542/peds.2013-1071 
  13. Centers for Disease Control and Prevention. (2024, April). Common cold: Fact sheet. U.S. Department of Health and Human Services. Retrieved January 24, 2025, from https://www.cdc.gov/common-cold/media/pdfs/2024/04/CommonCold_fact_sheet_508.pdf 
  14. Centers for Disease Control and Prevention. (n.d.). About antimicrobial resistance. U.S. Department of Health and Human Services. Retrieved January 24, 2025, from https://www.cdc.gov/antimicrobial-resistance/about/index.html 
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  16. Cech NB, Junio HA, Ackermann LW, Kavanaugh JS, Horswill AR. Quorum quenching and antimicrobial activity of goldenseal (Hydrastis canadensis) against methicillin-resistant Staphylococcus aureus (MRSA). Planta Med. 2012 Sep;78(14):1556-61. doi: 10.1055/s-0032-1315042. Epub 2012 Jul 18. PMID: 22814821; PMCID: PMC4527992. 
  17. Vila Domínguez A, Ayerbe Algaba R, Miró Canturri A, Rodríguez Villodres Á, Smani Y. Antibacterial Activity of Colloidal Silver against Gram-Negative and Gram-Positive Bacteria. Antibiotics (Basel). 2020 Jan 19;9(1):36. doi: 10.3390/antibiotics9010036. PMID: 31963769; PMCID: PMC7167925. 
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  19. Tulstrup MV, Christensen EG, Carvalho V, Linninge C, Ahrné S, Højberg O, Licht TR, Bahl MI. Antibiotic Treatment Affects Intestinal Permeability and Gut Microbial Composition in Wistar Rats Dependent on Antibiotic Class. PLoS One. 2015 Dec 21;10(12):e0144854. doi: 10.1371/journal.pone.0144854. PMID: 26691591; PMCID: PMC4686753. 
  20. Knoop KA, McDonald KG, Kulkarni DH, Newberry RD. Antibiotics promote inflammation through the translocation of native commensal colonic bacteria. Gut. 2016 Jul;65(7):1100-9. doi: 10.1136/gutjnl-2014-309059. Epub 2015 Jun 4. PMID: 26045138; PMCID: PMC4670297. 
  21. Wang G, Feng D. Therapeutic effect of Saccharomyces boulardii combined with Bifidobacterium and on cellular immune function in children with acute diarrhea. Exp Ther Med. 2019 Oct;18(4):2653-2659. doi: 10.3892/etm.2019.7836. Epub 2019 Jul 31. PMID: 31572514; PMCID: PMC6755444. 
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  23. Yoo S, Jung SC, Kwak K, Kim JS. The Role of Prebiotics in Modulating Gut Microbiota: Implications for Human Health. Int J Mol Sci. 2024 Apr 29;25(9):4834. doi: 10.3390/ijms25094834. PMID: 38732060; PMCID: PMC11084426. 
Dr. Green Mom

Dr. Mayer is a naturopathic medical doctor and an expert in nutrition and wellness as it relates to pediatrics and families. Her passion for prevention of disease as cure fueled her desire to immerse herself into specializing in adult onset chronic conditions as well as childhood chronic illness.

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